hrp0082p1-d2-218 | Reproduction (1) | ESPE2014

High Incidence of Genetic Defects in a Cohort of 24 Male Adolescents with Persistent Pubertal Gynecomastia

Paris Francoise , Gaspari Laura , MBou Felicien , Philibert Pascal , Lauber-Biason Anna , Sultan Charles

Background: Pubertal gynecomastia is a common condition appearing in up to 65% of adolescent boys. However, if male breast development is over B3–B4 and lasts more than 2–3 years, persistent pubertal gynecomastia (PPG) may be the sign of serious endocrine disease and the source of considerable psychological discomfort.Objective and hypotheses: We investigated a cohort of 24 adolescents with PPG followed at the Pediatric Endocrinogy Unit over a ...